What is Withdrawal from Fioricet Like?

Fioricet is a combination medication that contains three medicines: butalbital, acetaminophen, and caffeine.

Doctors prescribe this medicine to people who struggle with headaches, particularly tension headaches. It’s the 187th most-prescribed medication in the United States.2 Doctors prescribed an estimated 3.1 million prescriptions for Fioricet in 2019.

While the medicine is legal, some people abuse it illegally– the following information will outline Fioricet, signs of addiction and abuse, and treatment.

Is Fioricet Addictive?

Fioricet has the potential to be addictive. Doctors do not recommend taking it more than twice a week, as taking the drug more often can increase the potential of addiction and abuse.3 Developing a tolerance to Fioricet is possible. Withdrawal symptoms can occur if the drug is taken too often and then suddenly stopped.

Addiction to a substance like Fioricet causes a loss of control over how much and how often the drug is taken. While addiction may initially be easy to conceal, it ultimately causes problems in daily life, often from a financial, work, family, or friends standpoint.

Is Fioricet Safe?

It’s a safe medication when taken as a doctor recommends. There is a risk for overdose including when taken with other medications, such as opioid painkillers. A risk for acetaminophen overdose exists, as well.3 This can cause life-threatening liver damage.

Due to safety concerns, the medication is banned in most European countries.

How Fioricet Used?

Doctors prescribe it to relieve tension headaches.3 This headache type causes tension and pressure in the neck and scalp.3 Some people who experience tension headaches describe the feeling as if they have a rubber band wrapped around their head and the rubber band is squeezing tightly around them.3

In many instances, tension headaches can be resolved with non-prescription medications. Examples of ways to relieve tension headaches include drinking plenty of water, reducing stress, resting, and taking over-the-counter pain-relieving medications, such as acetaminophen or ibuprofen. However, these medicines sometimes don’t provide relief for tension headaches. As a result, doctors may prescribe Fioricet.

When doctors prescribe the medication, they usually intend it as a short-term remedy, or as-needed for headaches.3 Doctors don’t usually intend the use of this the medication daily or past a few weeks when a history of tension headaches is prevalent.

Can You Overdose on Fioricet?

Yes, it is possible to overdose. Some of the symptoms that a person may be overdosing include the following:

  • Losing consciousness
  • Shallow breathing
  • Slowed or no breathing, which may cause a person to turn blue in appearance
  • Stomach pain
  • Sweating
  • Yellowing of the skin or eyes

These indicate a medical emergency, and 911 should be called at the first signs of overdose.

How Do I Stop Using Fioricet?

Fioricet usage should not be stopped without a doctor’s recommendation. Depending on the dosage, symptoms will vary in individual cases.

Talking to a doctor before stopping taking the medicine can help establish a treatment plan that reduces the risks of a withdrawal seizure.

What is Withdrawal from Fioricet Like?

If Fioricet has been abused, withdrawals will usually begin about eight to 36 hours after the last dose of Fioricet taken.3 Doctors usually recommend a medical treatment facility for withdrawal because as a central nervous system depressant, Fioricet can cause life-threatening seizures.3

Other withdrawal symptoms that a person can go through after abusing Fioricet include:

Treatment for Fioricet Abuse

Fioricet can cause symptoms that are similar to excess alcohol consumption. Its withdrawal symptoms also closely resemble those of alcohol withdrawals, according to an article in the journal JAMA Neurology.

Those who struggle with Fioricet abuse should seek treatment at a medical facility, such as a hospital or rehabilitation facility. There, a doctor can establish a tapering plan, slowly stopping the dosage. Tapering the medication is extremely important to avoid a higher risk for seizure. According to JAMA Neurology, most doctors will recommend reducing a person’s overall daily dose by ten percent a day until the person stops taking the medicine entirely.

Benzodiazepines, such as midazolam, may be prescribed for those withdrawing from Fioricet. This reduces the risk of a withdrawal seizure. However, it is still always possible that a seizure may occur.

Addiction can be more than just a physical dependence on a particular drug-there may be a mental connection to how the medication makes the person feel. When this is the case, it’s important to seek counseling and sometimes a support group that can help navigate the strong cravings present for the drug. A counselor or therapist can help teach other, healthier ways of coping with anxiety or headaches that can reduce the risks of a return to Fioricet abuse.


Fioricet is a headache medicine intended for infrequent use but has been abused as a remedy to treat headaches or as a means to increase the relaxation and slowed-down feelings that alcohol or illegal drugs can produce. While it is not on the drug schedule across the country, some states have it on their drug schedule. This means the substance may be more tightly controlled for prescribing across those particular states.

If you or someone you love suffers from Fioricet addiction, seek medical treatment. Trying to withdraw or quit “cold turkey” could cause seizures, which may be life-threatening.