Are there any negative side effects of the pain killer Fioricet?

Are there any negative side effects of the pain killer Fioricet?
My doctor prescribed Fioricet to me for my migraines. My Rx says that I can take 2 pills – 4 times a day. Are there any known long term side effects from using this drug? I take them pretty regularly.

Best answer:

Fioricet Side Effects

Fioricet Side Effects

Frequently Observed Fioricet Side Effects

The most frequently reported adverse reactions are drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling.

Infrequently Observed Fioricet Side Effects

All adverse events tabulated below are classified as infrequent.Central Nervous System: headache, shaky feeling, tingling, agitation, fainting, fatigue, heavy eyelids, high energy, hot spells, numbness, sluggishness, seizure. Mental confusion, excitement, or depression can also occur due to intolerance, particularly in elderly or debilitated patients, or due to overdosage of butalbital. Autonomic Nervous System: dry mouth, hyperhidrosis. Gastrointestinal: difficulty swallowing, heartburn, flatulence, constipation. Cardiovascular: tachycardia. Musculoskeletal: leg pain, muscle fatigue. Genitourinary: diuresis. Miscellaneous: pruritus, fever, earache, nasal congestion, tinnitus, euphoria, allergic reactions. Several cases of dermatological reactions, including toxic epidermal necrolysis and erythema multiforme, have been reported. Fioricet contains a combination of acetaminophen, butalbital, and caffeine Acetaminophen is a pain reliever and fever reducer. Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow. Fioricet (butalbital, acetaminophen, and caffeine) is a combination pain reliever and muscle relaxant used in the treatment of tension headache and migraine, even any kinds of headache. It is available as a generic prescription. Generic Fioricet is much cheaper than Brand Fioricet but they almost have the same effects and same side effects. The most frequently reported adverse reactions or side effects of fioricet are: drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling.

Common side effects of Fioricet oral:

Irritation of the Stomach or Intestines Less Severe
Drowsiness Less Severe
Dizzy Less Severe

Infrequent side effects of Fioricet oral:

Depression Severe
Sluggishness Severe
Confused Severe
Over Excitement Severe
Nightmares Less Severe
Incomplete or Infrequent Bowel Movements Less Severe
Feeling Faint Less Severe
Sensation of Spinning or Whirling Less Severe
Chronic Trouble Sleeping Less Severe
Head Pain Less Severe
Feel Like Throwing Up Less Severe
Throwing Up Less Severe
Nervous Less Severe
Easily Angered or Annoyed Less Severe
Anxious Less Severe

Rare side effects of Fioricet oral:

Discolored Spots and Small Elevations of the Skin Severe
Acute Pustular Eruptions on Skin Severe
Extra Heartbeat Severe
Feeling of Throat Tightness Severe
Acute Liver Failure Severe
Hepatitis Severe
Hepatitis caused by Drugs Severe
Inflammation of Skin caused by an Allergy Severe
Toxic Epidermal Necrolysis Severe
Stevens-Johnson Syndrome Severe
Skin Rash with Sloughing Severe
Decreased Calcification or Density of Bone Severe
Loss of Memory Severe
Hallucination Severe
Rash Severe
Wheezing Severe
Trouble Breathing Severe
Life Threatening Allergic Reaction Severe
Giant Hives Severe
Reaction due to an Allergy Severe
Rickets Severe
Megaloblastic Anemia Severe
Decreased Blood Platelets Severe
Deficiency of Granulocytes a Type of White Blood Cell Severe
Decreased White Blood Cells Severe
Decreased Neutrophils a Type of White Blood Cell Severe
Taking Habit Forming Drugs Less Severe
Feeling Restless Less Severe
Blind Spot in the Eye Less Severe
Perform Complex Natural behaviors while Asleep Less Severe
Increased Feeling of the Skin Less Severe
Ringing in the Ears Less Severe
Hives Less Severe
Involuntary Quivering Less Severe
Uncoordinated Less Severe
Fast Heartbeat Less Severe

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat;
  • feeling light-headed or short of breath;
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms.

Less serious side effects may include:

  • drowsiness;
  • dizziness, confusion or lightheadedness;
  • dry mouth;
  • nausea, vomiting, stomach pain, loss of appetite;
  • feeling anxious or jittery;
  • drunk feeling; or
  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.